The FDA recently approved Esketamine, a medication which is available from Janssen Neuroscience under the brand name Spravato.

Spravato is available only through a restricted program known as the Spravato REMS (Risk Evaluation and Mitigation Strategy) because of serious adverse outcomes that can be associated with the use of the medication including sedation, dissociation, abuse, misuse, and elevated blood pressure.

Spravato is FDA approved for adult patients (18 years or older) to be used in combination with another antidepressant medication for patients who suffer from Treatment Resistant Depression. It is administered as a nasal spray twice weekly for the first 4 weeks of treatment, then once weekly for 3 weeks, then once every 1-2 weeks thereafter.

This is a medication that can only be given in a clinic setting where patients can be medically monitored for at least 2 hours after administration. This requirement is part of the Spravato REMS program mentioned above which is in place due to the following possible side effects:

Risk of sedation and dissociation –
In clinical trials, 49%-61% of patients developed sedation and 0.3% of patients experienced a loss of consciousness. Dissociative or perceptual changes occurred in 61% – 75% of patients. The effect typically starts about 40 minutes after administration. Cognitive impairment typically clears in about 2 hours, but sleepiness may take 4 hours to clear. Patients should not drive or engage in any other potentially dangerous activities until the following day after a normal period of sleep.

Potential for abuse and misuse –
Spravato is a schedule III controlled substance, individuals with a history of substance abuse or dependence may be a greater risk for abuse and misuse of this medication.

Risk for an increase in blood pressure –
Blood pressure typically peaks about 40 minutes after administration. Approximately 8%-17% of patients experienced an increase of more than 40 mmHg in systolic BP and/or 25 mmHG in diastolic BP in the first 1.5 hours after administration. As a general rule, Spravato therapy may be delayed if pre-treatment BP is >140/90.

The most common side effects experienced by patients treated with Spravato in the clinical trials were disassociation, dizziness, nausea, sedation, vertigo, decreased feeling or sensitivity (hypoesthesia), anxiety, lethargy, increased blood pressure, vomiting and feeling drunk.

Based on the requirements of the Spravato REMS Program, Indiana Health Group is not offering this therapy at our office at the present time. Although we are interested in this novel form of treatment, at present time we do not have the space or additional medical staff that would be necessary to safely and effectively provide this form of treatment in compliance with the requirements of the program. We will continue to evaluate this and will determine if we may be able to offer this treatment at our office at some point in the future.

For now, we will make every effort to assist interested patients who may be appropriate candidates for this treatment to other local facilities who are able to provide this as we become of aware of them.

Best regards,

Indiana Health Group

IHG welcomes William Jones, MD to the practice!

Indiana Health Group welcomes

William B. Jones, MD

Dr. Jones specializes in the treatment of: ADD/ADHD, Bipolar Disorder, Depression, Mood Disorders, and Panic Disorders.

Dr. Jones is currently in network with Anthem.  Other network applications are pending and we will update the website accordingly.




Now offering Zilis UltraCell CBD TOPICAL!

Introducing our newest UltraCell product!

UltraCell Full Spectrum Hemp CBD Topical

UltraCell Full Spectrum Hemp CBD Topical combines our trademarked, full spectrum CBD hemp oil with a proprietary blend of essential oils to help soothe and relax away aches and pains. Organic aloe gives our Topical a luxurious feel and leaves your skin feeling silky. The balance of essential oils, including black pepper, chamomile, and peppermint with UltraCell CBD hemp oil helps create harmony to ease your mind and body.


Coming this Spring – BioTe Hormone Therapy

Signs & Symptoms of Hormone Imbalance

BioTE® Medical was developed to alleviate the myriad of issues that can arise from hormone imbalance. Learn about the signs and symptoms of hormonal imbalance below.

What are the signs and symptoms of low testosterone in men?

A low level of testosterone in a man means more than just a low sex drive or erectile dysfunction (ED). Symptoms consistent with low testosterone are:

  • Low sex drive
  • Erectile Dysfunction (ED)
  • Chronic fatigue
  • Loss of muscle mass
  • Increased body fat (especially in the waist area)
  • Decreased bone mass
  • Mood changes
  • Lower mental capacity
  • Depression
  • Irritability
  • Brain Fog

Additionally, studies have shown there are some conditions that are consistent with low levels of testosterone including:

  • Diabetes
  • Cardiovascular Disease
  • Depression
  • Stress
  • Anxiety
  • Alcohol use
  • High Cholesterol

What are the signs and symptoms of hormonal imbalance in women?

There are a variety of symptoms from hormone imbalance in women including:

  • Fatigue
  • Night Sweats
  • Hot flashes
  • Decreased sex drive
  • Weight gain
  • Insomnia
  • Irritability
  • Anxiety
  • Depression
  • Cold hands and feet

If your menstrual cycle has stopped before menopause, or if you are experiencing this or any other symptom of menopause, you may have low estradiol. An increase in UTIs, depression or painful intercourse may also indicate low estradiol in women.

I can identify with these sypmtoms, what do I do next? How do I get started?

Contact our office at 317.843.9922 or email


Click here for additional information on BioTe Medical


Zilis UltraCell CBD Oil – Now Available!


What is CBD?
The plant genus Cannabis contains two unique plant species — Hemp (Male), a tall cane-like plant that originated in Central Asia and is now cultivated worldwide; and Marijuana (Female),  hemp’s shorter, leafier, cousin. Cannabis naturally produces more than 80 chemical compounds, called cannabinoids. The two most common are tetrahydrocannabinol (referred to as THC) and cannabidiol (CBD.) THC is the compound responsible for psychoactive effects. Cannabis plants with high THC content are considered marijuana; while plants with less than 1% THC are considered hemp.

Will CBD Oil get you high?
NO! CBD oil is not psychoactive because it contains VERY low amounts of THC (<0.3%), which is the cannabinoid responsible for making users feel “high”. It is a health supplement can be used by just about everyone needing a better quality of life!

Is CBD Legal?
Zilis UltraCell is industrial Hemp CBD oil that is US Farm Bill Compliant (Section 7606), and is not a controlled substance. It is Legal in all 50 states.
The FDA considers hemp oil (and CBD) to be a dietary supplement (not a medication). In the US, you don’t need a prescription and can legally purchase and consume Cannabidiol in any state.

Where does Zilis UltraCell CBD Oil come from?
Zilis UltraCell sources their hemp oil from an certified USDA organic producer in Colorado. They use a proprietary science combining the best of liposome and micelle technology which allows for 100% bio availability.

What are the benefits?
Although this supplement is not designed to cure any symptoms or diseases, and due to FDA regulations NO product claims can be made as a “cure” for specific diseases. Hemp CBD oil has been studied and shown to promote relaxation and provide benefits with:

  • Anxiety & Stress
  • Pain & Joint Function
  • Sleep
  • Health Heart Functions
  • Urinary Tract Health
  • Healthy Lung Function
  • Cholesterol Level
  • Circulatory System                             

It is recommended to take 1ml Zilis UltraCell, per day.
We recommend placing the oil under your tongue and holding it for 10-15 seconds, then swallowing. This allows your body to properly absorb the UltraCell oil and distribute it throughout the body.

What does Zilis Ultracell Cost?
The cost on Zilis website is $150. Suggested retail price through many distributors is $139.  Our office is able to offer this to our patients at the minimum allowable price of $120 with FREE SHIPPING!

Where can I purchase UltraCell?

  • Calling our office at:  317.843.9922
  • In our office located at: 703 Pro-Med Lane, Carmel, IN 46032 

Click HERE to view our flyer!

We’d appreciate your feedback!

Thank you for choosing Indiana Health Group for your behavioral health needs.  We hope that your experience with our office has been pleasant.

As a part of our ongoing effort to provide better services, we would like to request your feedback via a short online survey.

In order to take the survey, please click here: IHG Patient Satisfaction Survey

We strive to treat our patients as we would like to be treated; with respect, courtesy and compassion.  We are grateful for your participation.  We are listening and committed to making your experience at Indiana Health Group the best that it can be.

Have a wonderful day!

The Staff of Indiana Health Group


IHG is excited to announce the return of EMDR treatment!  Contact our office to set up an appointment with Kim Keller.

Happy Holidays!

Indiana Health Group will be CLOSED on the following dates:

Christmas:  December 25th & 26th.  We will reopen on Wednesday, December 27th.

New Years:  January 1st.  We will reopen on Tuesday, January 2nd.

In the event of an emergency, please call 911 or go directly to the nearest emergency room.

Thank you.